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The Top 5 Hemp Cannabinoids You Need to Try Today

March 31, 2025
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Different cannabinoids influence mood, focus, and relaxation based on their interaction with your body.

THCa is a raw cannabinoid that won’t get you high unless it’s decarboxylated or heated through smoking, vaping or aging.

Delta-8 and HHC provide a smoother, less intense high compared to traditional Delta-9 THC.

CBG has the potential to support brain health, while THCp delivers stronger, more potent effects than THC.

Cannabis isn’t just about getting high—it’s a complex plant packed with compounds that do way more than most people realize. If you’ve ever noticed that certain strains make you feel relaxed while others boost your focus, that’s no accident. Just like finding the perfect group of friends, the right cannabinoids interact with your body and shape your experience in ways that match what you need.

With over 100 cannabinoids identified so far, some stand out for their effects and potential benefits. Understanding how they work can help you choose the right products for what you’re looking for—whether it’s to chill out, stay sharp, or just feel better overall. Let’s dive into the top five cannabinoids, why they matter, and how they can elevate your cannabis experience.

What Are Cannabinoids?

Before we get into the big players, let’s break it down. Cannabinoids are natural compounds found in cannabis that interact with your body’s endocannabinoid system (ECS). Think of the ECS as your body’s built-in control center—it helps regulate mood, sleep, appetite, and overall balance.

When cannabinoids enter your system, they bind to specific receptors and trigger different effects. That’s why one strain might put you in a creative flow while another has you melting into the couch.

Now, let’s meet the true stars of the cannabinoid world:

1. THCa (Tetrahydrocannabinolic Acid) – The One That Needs a Little Heat

What it is: THCa is the raw, unheated form of THC. Unlike its decarboxylated cousin, THCa doesn’t cause a high on its own.

What it does:

  • May have anti-inflammatory properties
  • Potential neuroprotective effects
  • May support healthy sleep patterns

THCa is the cannabinoid you’ll find in fresh cannabis. It remains inactive unless heated (via a process called decarboxylation), which is why it doesn’t cause any psychoactive effects unless you smoke or vaporize the plant.

However, once heated through smoking, vaping, or baking, THCa converts to Delta-9 THC for a familiar mind and body high. This conversion has earned THCa the nickname “legal weed”, as it complies with the federal farm bill at the time of sale, yet converts to traditional THC when smoked.

2. HHC (Hexahydrocannabinol) – The One With the New Buzz

What it is: HHC is like THC, but with a little twist. It’s chemically similar, but it can feel a bit different when you use it.

What it does:

  • Produces mild euphoria
  • May enhance mood and relaxation
  • Less potent than traditional THC, with potential for reduced anxiety

HHC might not be the first cannabinoid that comes to mind, but it’s quickly making its way onto the scene. It’s been described as having a similar effect to THC but with a smoother, less intense high. As a lesser-known compound, HHC could be a great option for those looking for mild effects with fewer worries about overwhelming experiences.

3. Delta-8 (Delta-8-Tetrahydrocannabinol) – The One With a Little Less Intensity

What it is: Delta 8 is a type of cannabinoid that comes from THC, but it’s a little different. Think of it as a “gentler” version of the regular THC (Delta 9) that most people know. It gives you a similar feeling but isn’t as strong.

What it does:

  • Mild euphoria and relaxation
  • Can offer calming effects without the intense high
  • May help with anxiety or stress

For those who enjoy the benefits of THC but find the effects of Delta 9 a bit too strong, Delta 8 offers a more manageable option. It provides the euphoria and relaxation you’d expect from cannabis without leaving you feeling overwhelmed. If you’ve ever wished you could enjoy the benefits of THC but without the intensity, Delta 8 might be the answer.

4. CBG (Cannabigerol) – The One Where It All Begins

What it is: CBG is often called the “mother of all cannabinoids” because it’s the precursor to other major cannabinoids like THC and CBD.

What it does:

  • Supports a healthy inflammatory response
  • May promote digestive health
  • Supports brain health and cognitive function

CBG is gaining recognition for its potential therapeutic benefits. While it may not have the same fame as THC or CBD, its role in the cannabis plant is critical. It’s the starting point for many cannabinoids, and as research expands, CBG may prove to be a powerhouse for wellness, especially when it comes to managing inflammation and supporting the brain.

5. THCp (Tetrahydrocannabiphorol) – The One That Hits Harder

What it is: THCp is like THC’s bigger sibling. It works in a similar way but is much better at connecting with the parts of your body that make you feel the effects of cannabis. So, it can make you feel things more strongly than THC does.

What it does:

THCp is still a newcomer to the cannabis world, but it’s showing promise as being significantly more potent than regular THC. Its powerful effects could offer more intense relief and relaxation, making it a potentially game-changing cannabinoid for those who seek stronger effects. It’s a cannabinoid to watch as more studies are conducted.

What About the Other Cannabinoids?

The exact number of cannabinoids is still unknown, with estimates ranging from over 100 to approximately 177 distinct compounds identified to date. While THC and CBD get most of the attention, many lesser-known cannabinoids play important roles in shaping the effects of cannabis. Some other noteworthy ones include:

  • THCV (Tetrahydrocannabivarin): Often called “diet weed” because it’s being studied for its potential to suppress appetite. It may also promote energy and focus, making it an intriguing option for productivity.
  • CBDV (Cannabidivarin): A close relative of CBD that’s being explored for its potential effects on neurological conditions.
  • CBL (Cannabicyclol): A breakdown product of CBC that researchers are still investigating for its properties.
  • CBE (Cannabielsoin): A lesser-known metabolite of CBD that remains under scientific study.
  • CBT (Cannabitriol): Rare and not well understood yet, but an intriguing part of the cannabinoid spectrum.

Beyond these, researchers continue to discover and analyze new cannabinoids, each with its own potential effects and benefits. Some cannabinoids interact directly with CB1 and CB2 receptors, while others work more subtly within the endocannabinoid system. The more we learn, the more we realize that cannabis is far more complex than just THC and CBD.

As cannabinoid research progresses, we may find new therapeutic applications, better-targeted cannabis products, and even novel cannabinoids that redefine how we use cannabis for wellness, relaxation, and medicinal purposes. The next breakthrough in cannabis science could come from one of these under-the-radar compounds.

The Finale: The One Where You Find Your Perfect Cannabinoid

Whether you’re looking to unwind, stay focused, or make the most of your cannabis experience, understanding cannabinoids can truly enhance your journey. THC, CBD, CBG, Delta 8, THCp, and HHC are some of the key players, but they’re just the tip of the iceberg—cannabis is a rich plant with so much more to explore.

Next time you’re selecting a product, take a moment to check the label and see which cannabinoids are included. The right one will be there, ready to help you relax, boost your focus, or strike the perfect balance. Who knows? You might just discover your new best friend.

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References

What are cannabinoids?

Cannabinoids are natural compounds in cannabis that interact with your body’s endocannabinoid system, influencing mood, relaxation, focus, and overall well-being.

Does THCa get you high?

Yes. While THCa is non-psychoactive until heated, once decarboxylated, it converts into THC, producing the euphoric effects commonly associated with cannabis.

How is Delta-8 different than Delta-9 THC?

Delta-8 offers a milder, smoother high than Delta-9, with less intensity and potential for reduced anxiety or paranoia.

What makes THCp stronger than Delta-9 THC?

THCp binds more strongly to cannabinoid receptors, making its effects significantly more intense than regular THC.

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