The legalization of hemp gave way to many new cannabinoids to hit the market. And if you’ve been around the cannabis block, you’ve probably heard of THC-o. The so-called “spiritual cannabinoid” is making waves within the hemp community. But what is it? And what are the true effects of THC-o? In today’s blog, we’ll discern truth from myth and discuss everything THC-o, from how it works in the body, what the high feels like, possible perks, and potential downfalls. Let’s get hemping!
What Is THC-o?
THC-o, also called THC-o acetate, is one of the synthetic cannabinoids that’s been turning heads lately! It’s a THC analog, meaning it’s similar to regular THC, but rumor has it, it’s about three times stronger!
Like other psychoactive cannabinoids, THC-o works by interacting with the body’s endocannabinoid system (ECS). The ECS is like the body’s control center for things like mood, sleep, and appetite. THC-o binds to CB1 receptors in your brain and central nervous system, just like regular THC. This connection triggers the release of dopamine, which gives you that familiar euphoric or “high” feeling.
Effects of THC-o
THC-o is a pretty unique cannabinoid, and if you’re familiar with regular Delta-9 THC, imagine something that’s about three times stronger! THC-o is a powerful THC analog that can create all sorts of effects, ranging from deep relaxation to some wild psychedelic experiences.
If you’re into something a bit more adventurous, THC-o’s psychedelic effects might be just what you’re looking for. Some users compare it to the experience of “magic mushrooms,” offering a trippy, mind-expanding journey. Of course, this might be a pro or a con, depending on what kind of experience you want.
Looking to chill out? THC-o is also known for its calming and mood-boosting effects. Many people feel relaxed and at ease after using it, which is perfect after a long, stressful day. Plus, it might help ease discomfort and inflammation, although studies are still ongoing, a user survey reported “feeling relief from various aches and discomfort”.
Now, if you’re someone who struggles with sleep, THC-o might just help you catch some extra Z’s. Even though research on THC-o specifically is still developing, we know that Delta-9 THC can support better sleep. Since THC-o is much stronger, there’s a good chance it could help you fall asleep faster and stay asleep longer. Many users have said it works like a charm for getting a good night’s rest!
What Is The THC-o High Like?
The THC-o high takes you on a journey that’s either exciting or deeply relaxing, depending on how much you take and your THC tolerance. In small doses, it could feel like Delta-8 THC. However, in high doses, that’s a different story!
The full-on THC-o experience starts off feeling a lot like Delta-9 THC. There’s that familiar wave of euphoria, your body starts to feel light and tingly, and your mind gets a little hazy in the best way. But THC-o has an edge: its effects can go beyond the usual high and dip into the “psychedelic” territory, especially with higher doses.
As the high settles in, many people describe feeling a warm, airy head high. Your thoughts might feel a bit slower but in a calm, dreamy way. It’s not the kind of high that makes you anxious or restless, it’s more like you’re floating through the day without a care in the world. You’ll probably feel super relaxed, but still very aware and connected to your surroundings.
Once THC-o really kicks in, it starts to show off its unique effects. Imagine feeling like a wide-eyed kid again where everything seems fascinating, and you get this playful curiosity that makes you want to explore and engage with whatever’s around you. Colors might look a little brighter, textures more interesting, and you may catch yourself smiling for no reason at all.
For some, the high can take on a more visual turn. You might experience mild hallucinations or a slight distortion in how you see things, which adds to the whole “psychedelic effects.”
One thing to keep in mind: the munchies can hit hard! So, don’t be surprised if you suddenly find yourself craving your favorite snacks. But remember, each person is unique, and this experience while common may be different for you, so proceed with caution.
How Is THC-o Made?
Even though THC-o is a lab-made cannabinoid, it starts with something natural: hemp-derived cannabinoids. The process kicks off with extracting CBD or THC from the hemp plant. Then, labs convert these cannabinoids into Delta-8 THC.
Next, they combine Delta-8 THC with acetic anhydride, a chemical compound that transforms it into THC-o. While acetic anhydride can be hazardous on its own, skilled labs ensure they handle it safely, resulting in a potent and safe cannabinoid. So, don’t try this at home, or buy THC-o from unknown brands.
THC-o vs Traditional THC
THC-o and traditional THC may share some family resemblance, but each has its own unique quirks. Sure, they’re cousins in the cannabinoid world, but they’re not identical!
First off, traditional THC, the psychoactive superstar of cannabis, is natural and comes straight from cannabis plants. On the other hand, THC-o is a synthetic cannabinoid, crafted in a lab to pack a punch. In fact, THC-o is about three times stronger than its natural cousin, which is quite a claim to fame!
While traditional THC delivers a potent experience that many enjoy (and some fear), it generally stays within familiar, euphoric boundaries. THC-o, however, takes things up a notch, venturing into full-on psychedelic territory.
THC-o vs Delta-8 THC
Delta-8 THC is a naturally occurring cannabinoid found in the hemp plant. However, it appears in such tiny amounts that brands often need to get creative. They extract it from CBD through isomerization (a fancy term for tweaking CBD’s molecular structure to transform it into Delta-8.) This process makes Delta-8 somewhat semi-synthetic, but it still keeps that plant-derived origin.
Unlike Delta-8, THC-o doesn’t naturally occur in the hemp plant at all. Instead, it’s derived from Delta-8, meaning it gets a little boost along the way.
When it comes to the effects, Delta-8 delivers a mellow experience. Imagine a cozy body high that keeps your mind clear and relaxed. It’s like enjoying a gentle hug from your couch. In contrast, THC-o packs a punch! With effects that are around five times stronger, it offers an ultra-potent high that envelops both your body and mind. It’s like an electrifying wave of euphoria that makes you feel like you’re floating on a cloud.
Is THC-o Legal?
Thanks to the Farm Bill, hemp and all its cannabinoids came off the controlled substances list, but with one little catch: the final product can’t contain more than 0.3% Delta-9 THC by total dry weight. But, each state can still make its own rules, restricting the sale and use of these hemp products.
This bill led many to think THC-o, despite being synthetic, was still a hemp-derived baby, making it federally legal. After all, it’s synthesized from hemp cannabinoids! It seemed like a win for all the cannabis enthusiasts. Then comes the plot twist. The DEA came in to clarify that THC-o doesn’t occur in hemp naturally, so it’s not a hemp derivative. Surprise! THC-o falls into the controlled substances category.
In February 2023, cannabis attorney Rob Kight spilled the tea, showcasing his correspondence with the DEA confirming that THC-o is indeed a controlled substance. So, what does this mean for you? Well, on a federal level, THC-o is illegal. However, it may still have a home in states that have legalized recreational cannabis.
Side Effects of THC-o
While THC-o can offer a unique psychoactive experience, it’s not without its drawbacks.
First and foremost, inhalation poses the greatest risk. While THC-o itself isn’t generally harmful, using inhalable methods, like vapes, flower, or dab rigs, can introduce risks. This is because THC-o is the acetate-ester form of THC. According to studies, When you heat THC-o, it can produce ketene, a toxic gas linked to serious lung injuries. So, always be mindful of how you consume it!
Aside from inhalation risks, you might encounter some common side effects. Users often report experiencing dry mouth and eyes, low blood pressure, and lightheadedness. Additionally, sleepiness, disorientation, and changes in how you perceive colors and brightness are also possible.
THC-o Products Available Today
Want to try out THC-o? You’re in for a treat! There are plenty of cannabis products that come infused with THC-o
First up, gummies! These tasty bites offer a fun and discreet way to enjoy THC-o. With various flavors, they’re perfect for satisfying your sweet tooth while getting your dose.
But it doesn’t stop there, there’s still THC-o Edibles! Such as chocolates, candies, and even baked goods.
Prefer versatility? THC-o tinctures can be dropped under your tongue or added to drinks for a customizable experience.
Though we wouldn’t recommend it, pre-filled THC-o cartridges and concentrates are available. Remember, heating THC-o isn’t a good idea.
Safely Dosing THC-o
When diving into the world of THC-o, it’s best to start small, think of it as dipping your toes into a pool before taking the plunge. Since THC-o packs quite the punch, we recommend beginning with a very low dosage to gauge your tolerance.
To calculate your perfect starting point, you can use this simple formula: (0.025)×(your body weight in lbs.)=your daily THC-o dosage in mg.
Don’t be surprised if the resulting number is on the low side! Given THC-o’s potency. Starting small allows you to ease into the experience without overwhelming your senses. And while this formula isn’t a one-size-fits-all, it could be a good start. Remember that each body is different.
As you explore THC-o, pay attention to how you feel. Gradually adjust your dosage, up or down, as you go. So, start low, and find your sweet spot!
Final Thoughts: THC-o High Effects
In conclusion, THC-o is a synthetic THC analog, it packs a punch that users report is 3x that of THC. It comes with a high that can range from upbeat and calming to downright psychedelic, depending on your THC tolerance. In small doses, THC-o offers a light, euphoric high, similar to that of Delta-9. You might feel relaxed, maybe a little giggly, but still totally in control.
However, when you up the dosage, things can take a trippy turn. Larger amounts of THC-o can have intense effects, often described as psychedelic. Think vivid visuals, deep introspection, and a sense that you’re floating through space (without ever leaving your couch). It’s definitely a different kind of high than what you’d get from regular Delta-9 THC.
But with all good things comes a downside. THC-o is federally illegal according to the DEA. Also, studies show that when heated, THC-o can produce a harmful chemical that you want to avoid.
Happy Hemping!

Legal Disclaimer:
By reading this information presented, you agree to release the author of any liability that comes from using this data. This post does not constitute legal advice. Claims about cannabinoids
Other Articles You Might Be Interested In
- THCp vs THC-o
- THCp Gummy Review – What to Expect
- Delta-8 THC vs THCp
- Is Delta-10 synthetic?
- Is Delta-8 legal in South Carolina?
References:
- Hemp Production and the 2018 Farm Bill – 07/25/2019 | FDA
- The Controlled Substances Act (dea.gov)
- THC-o survey
- DEA on THC-o
- Clinical Study: Cannabinoids Act Via Distinct Receptors
FAQs on THC-o Effects
Yes! Since THC-O is a derivative of THC, it can be detected by standard drug tests that screen for THC.
THC-o is generally considered three times more potent than THC.
While not always, some users have reported experiencing hallucinations or altered states of consciousness when using THC-o. If you’re concerned for your mental health, please only start with small doses or consult a professional.
Yes, like other cannabinoids from the same family, THC-o can interact with certain medications. Consult with a healthcare professional before using THC-o if you are taking any medications.